David Lougheed GitHub
From May 2019 until August 2020, I worked as a software developer at the Canadian Centre for Computational Genomics (C3G) in Montréal.
I have a B.Sc. in Computer Science and Biology from McGill (graduated May 2019 with First Class Honours.)
Epigenetic variation impacts ancestry-associated differences in the transcriptional
response to influenza infection (2022 preprint)
Katherine A Aracena, Yen-Lung Lin, Kaixuan Luo, Alain Pacis, Saideep Gona, Zepeng Mu, Vania Yotova, Renata Sindeaux, Albena Pramatarova, Marie-Michelle Simon, Xun Chen, Cristian Groza, David Lougheed, Romain Gregoire, David Brownlee, Yang Li, Xin He, David Bujold, Tomi Pastinen, Guillaume Bourque, Luis B Barreiro. bioRxiv Preprint. DOI: 10.1101/2022.05.10.491413
baRcodeR: An open‐source R package for sample labelling (2020)
Yihan Wu, David R. Lougheed, Stephen C. Lougheed, Kristy Moniz, Virginia K. Walker, Robert I. Colautti. Methods in Ecology and Evolution. DOI: 10.1111/2041-210X.13405
Genome-wide microhomologies enable precise template-free editing of biologically
relevant deletion mutations (2019)
Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura, Miki Nagai, Shiori Matsuo, David Lougheed, Hidetoshi Sakurai, Megumu K. Saito, Guillaume Bourque & Knut Woltjen. Nature Communications. DOI: 10.1038/s41467-019-12829-8
Software & Projects
EpiVar Browser (2022)
A browser for exploring quantitative trait loci and their associations with genotype and ancestry. Part of an upcoming publication by Aracena et al. (currently in preprint; 2022)
A platform for storing, analyzing, and visualizing genomic and epigenomic data, created while working at C3G.
A utility for creating online databases for scientific data.
MHCut Browser (2019)
A browser for microhomologies at variant CRISPR/Cas9 cut sites. Part of a publication by Grajcarek et al. (2019)
McGill Network (2018)
A visualization tool and API for examining shared interests between McGill researchers.
Elbow Lake Trail Guide (2015, revised 2016)
An interactive trail guide app available on Android and iOS.